Bone morphogenetic protein for sinus augmentation.

Bone morphogenic proteins (BMP) are members of the family of transforming growth factors. Fifteen different BMP have been identified, all with varying degrees of cellular activity, including cartilageor bone-inductive properties. Two recombinant proteins are available: recombinant human bone morphogenetic protein (rhBMP)-2 and rhBMP-7. These products have been investigated as alternatives to autogenous bone grafts in a variety of clinical situations, including spinal fusions, fracture repair, treatment of bone defects, and reconstruction of maxillofacial conditions. Reconstruction in the maxillofacial region includes alveolar ridge augmentation, mandibular reconstruction, and maxillary sinus augmentation.